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Anakinra May Help Ease the Pain of Rheumatoid Arthritis
How Does Anakinra Work?
How Should I Take This Medicine?
What Are the Side Effects?
- Infections (anakinra suppresses the immune system)
- Flu-like symptoms
- Abdominal pain
- Low white blood cell count
Who Should Not Take Anakinra?
- Have a fever or think you may have an infection
- Are taking certain medicines, including TNF blockers (eg, adalimumab, etanercept, infliximab)
- Are allergic to proteins made from bacteria cells or any ingredient in the medicine
- Have a latex allergy
- Have asthma, HIV or AIDS, or kidney disease
- Are pregnant or breastfeeding
- Telling your doctor or dentist that you are taking anakinra before you have a procedure
- Talking to your doctor before you have a live virus vaccine
US Food and Drug Administration http://www.fda.gov
Arthritis Foundation http://www.arthritis.org/
The Arthritis Society http://www.arthritis.ca/
Canadian Pharmacists Association http://www.pharmacists.ca/
American Society of Health-System Pharmacists. Anakinra. PubMed Health website. Available at: http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000183. Updated February 1, 2009. Accessed September 12, 2012.
Anakinra (Kineret) FDA approved for use in rheumatoloid arthritis. American College of Rheumatology website. Available at: http://www.rheumatology.org/publications/hotline/1101anakinra.asp. Updated November 2001. Accessed September 12, 2012.
Bresnihan, B, Alvara-Gracia, JM, Cobby, M, et al. Treatment of rheumatoid arthritis with recombinant human IL-1 receptor antagonist. Arthritis Rheum 1998; 41:2196.
Anakinra. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php. Updated December 14, 2011. Accessed September 12, 2012.
Fleischmann, RM, Schechtman, J, Bennett, R, et al. Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial. Arthritis Rheum 2003; 48:927.
Patient information on anakinra. Austrailian Rheumatology Association website. Available at: http://www.rheumatology.org.au/downloads/anakinraCo-Badged15.09.pdf. Updated September 2011. Accessed September 12, 2012.
- Reviewer: Brian Randall, MD
- Review Date: 09/2012
- Update Date: 09/12/2012