Return to Index
Prosthetic Heart Valve Thrombosis
(Prosthetic Valve Thrombosis; PVT)
- Inadequate anticoagulant/blood thinning therapy after a valve transplant
- Prosthesis located at the mitral valve in the heart
- Atrial fibrillation
- Drugs such as contraceptives
- Cancerous tumors
- Systemic diseases such as systemic lupus erythematosus or inflammation and damage to various body tissues, including joints, skin, kidneys, heart, lungs, blood vessels, and brain
- Reduced cardiac pumping—possibly from heart failure
- Shortness of breath
- Difficulty breathing while lying down
- Difficulty exercising
- Chest pain, burning, or pressure
- Loss of consciousness
American Heart Association http://www.heart.org
National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov
Canadian Heart Research Centre http://www.chrc.net
Heart and Stroke Foundation of Canada http://www.heartandstroke.ca
Prosthetic heart valve thrombosis. DynaMed website. Available at: http://www.ebscohost.com/dynamed . Updated January 8, 2013. Accessed May 9, 2013.
Serpi M, Schmidt KG, Kreuz W, et al. Thrombolysis of prosthetic heart valve thrombosis using recombinant tissue plasminogen activator (rt-PA) in infancy and childhood. Z Kardiol. 2001;90(3):191-196.
Roudant R, Serri K, Lafitte S. Thrombosis of prosthetic heart valves: diagnosis and therapeutic considerations. Heart. 2007;93:137-142.