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Medications for Gestational Diabetes
- 95 milligrams per deciliter (mg/dL) [5.3 mmol/L] or less at fasting
- 140 mg/dL (7.8 mmol/L) or less one hour after a meal
- 120 mg/dL (6.7 mmol/L) or less two hours after a meal
- Metformin (eg, Fortamet, Glucophage)—works in the liver to lower the production of glucose and makes your body more sensitive to insulin
- Glyburide (eg, DiaBeta, Glynase, PresTab)—stimulates the body to make more insulin and helps the cells use the insulin better
- Take your medicine as directed. Do not change the amount or the schedule.
- Do not stop taking them without talking to your doctor.
- Do not share them.
- Know what the results and side effects. Report them to your doctor.
- Some drugs can be dangerous when mixed. Talk to a doctor or pharmacist if you are taking more than one drug. This includes over-the-counter medicine and herb or dietary supplements.
- Plan ahead for refills so you do not run out.
When to Contact Your Doctor
- Seizures or convulsions
- Recurrent or extreme low blood sugar
American Diabetes Association website. Available at: http://www.diabetes.org/ .
American Diabetes Association. Standards of medical care in diabetes 2010. Diabetes Care . 2010;33 Suppl 1:S11-61.
The American College of Obstetricians and Gynecologists. Diabetes and pregnancy. The American College of Obstetricians and Gynecologists website. Available at: http://www.acog.org/publications/patient%5Feducation/bp051.cfm . Accessed July 2010.
Gestational diabetes. The American College of Obstetricians and Gynecologists Practice Bulletin. No. 30. Sept. 2001.
Gestational diabetes mellitus. JAMA . 2001;286:2516-2518.
Gutzin S, Kozder E, Magee L, Feig D, Koren B. Safety of oral hypoglycemic agents in the first trimester of pregnancy: a meta-analysis. Can J Pharm. 2003;10(4):179-183.
Landon MB, et al. for MFMU Network: A multicenter, randomized trial of treatment for mild gestational diabetes. N Engl J Med. 2009;361:1339-1348.
Lexi-PALS. Glyburide. EBSCO Health Library, Lexi-PALS website. Available at: http://www.ebscohost.com/healthLibrary/ . Updated November 17, 2011. Accessed April 1, 2011.
Lexi-PALS. Metformin. EBSCO Health Library, Lexi-PALS website. Available at: http://www.ebscohost.com/healthLibrary/ . Updated February 17, 2011. Accessed April 1, 2011.
National Institute of Child Health & Human Development website. Available at: http://www.nichd.nih.gov/ .
Perkins JM, Dunn JP, Jagasia SM. Perspectives in gestational diabetes mellitus: a review of screening, diagnosis, and treatment. Clin Diabetes 2007;25:57-62.
Schroeder K. Medications for type 2 diabetes. EBSCO Health Library website. Available at: http://www.ebscohost.com/healthLibrary/ . September 9, 2010. Updated April 1, 2011.
Seiji TL, Brown AJ, Feinglos MN. Gestational diabetes mellitus. Clinical Diabetes. 2005; 23:17-24.
Standards of Medical Care in Diabetes 2006 III. Detection and diagnosis of gestational diabetes mellitus. Diabetes Care. 2006;29:S7
Turok DK, Ratcliffe SD, Baxley EG. Management of gestational diabetes mellitus. Am Fam Physician. 2003;68:1767-1772.
4/1/2011 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php : Dhulkotia JS, Ola B, Fraser R, Farrell T. Oral hypoglycemic agents vs insulin in management of gestational diabetes: a systematic review and meta-analysis. Am J Obstet Gynecol. 2010;203(5):457.e1-9.
- Reviewer: Andrea Chisholm, MD
- Review Date: 09/2013
- Update Date: 09/30/2013