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SexRx: Calcium Channel Blockers and Your Sex Life
Medications and Their Commonly Used Brand Names
What They Are Most Often Prescribed For:
How They Work:
Possible Sexual Side Effects:
How They May Cause Sexual Problems
Decreasing dopamine activity, which can lead to an increase in prolactin. Increased prolactin can have the following effects:
- Reduced sex drive
- Blocking the actions of excitatory peptides that are involved in genital sensation
Wait It Out
Change the Drug or Dose
Try an Antidote
- Sildenafil (Viagra)—This medicine is prescribed to men who have erectile dysfunction.
- Bupropion (Wellbutrin)—This is an antidepressant that is sometimes prescribed to help correct sexual problems.
Consider Herbal Supplements
American Heart Association http://www.heart.org/
National Institutes of Health http://www.nih.gov/
Canadian Urological Association http://www.cua.org/
Bupropion. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php. Updated April 11, 2011. Accessed August 1, 2012.
Crenshaw TL. Sexual Pharmacology: Drugs That Affect Sexual Function. WW Norton & Company; 1996.
Dusing R. Sexual dysfunction in male patients with hypertension: influence of antihypertensive drugs. Drugs. 2005;65(6):773-86.
Grimm RH Jr, Grandits GA, Prineas RJ, et al. Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS) Hypertension. 1997;29(1 Pt 1):8-14.
Hyperprolactinemia. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated March 5, 2012. Accessed August 11, 2012.
Mosenkis A, Townsend R. Gynecomastia and antihypertensive therapy. J Clin Hypertens. 2004;6(8):469-70.
Pena K, Rosenfeld J. Evaluation and treatment of galactorrhea. Am Fam Physician. 2001;63(9):1763-1771.
Sildenafil. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php. Updated April 11, 2011. Accessed August 1, 2012.
Tanner LA, Bosco LA. Gynecomastia associated with calcium channel blocker therapy. Arch Intern Med. 1988 Feb;148(2):379-80.
Yohimbe. EBSCO Natural and Alternative Treatments website. Available at: http://www.ebscohost.com/healthLibrary/ . Updated August 2011. Accessed August 11, 2012.
- Reviewer: Brian Randall, MD
- Review Date: 08/2012
- Update Date: 09/14/2012