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(Hyaluronic Acid Injection; Injection, Hyaluronic Acid)
Reasons for Procedure
|Joints Affected by Osteoarthritis|
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- Pain and swelling
- Infection at the injection site
- Allergic reaction to the hyaluronic acid or local anesthetic product
- Inflammation of the blood vessels (vasculitis)
- Having advanced OA
- Being 65 years or older
What to Expect
Prior to Procedure
- Taking pain medicines
- Getting injections of corticosteroids
- Doing physical therapy
- Losing weight
- Have x-rays done to determine the severity of your OA
- Ask you if you have any allergies (eg, chicken allergy) to the ingredients in the hyaluronic acid product
Description of the Procedure
How Long Will It Take?
Will It Hurt?
- To reduce pain and swelling, apply an ice pack. You may want to do this for 15-20 minutes, four times a day. Wrap the ice in a towel. Do not apply it directly to your skin.
- For the first two days, avoid straining your knee. Do not stand for a long time or do strenuous activity, like heavy lifting.
- Less knee pain
- Improved mobility
Call Your Doctor
- Signs of infection, including fever and chills
- Redness, swelling, increasing pain, bleeding, or discharge from the injection site
- Signs of allergic reaction (eg, hives , itching, difficulty breathing)
- Increased pain or swelling in the knee joint
American College of Rheumatology http://www.rheumatology.org/
The Arthritis Foundation http://www.arthritis.org/
The Arthritis Society http://www.arthritis.ca/
Canadian Arthritis Network http://www.arthritisnetwork.ca/
Arnold W, Fullerton D, Holder S, May C. Viscosupplementation: managed care issues for osteoarthritis of the knee. Academy of Managed Care Pharmacy website. Available at: http://www.amcp.org/data/jmcp/May07%5Fsuppl.pdf. Published May 2007. Accessed February 23, 2011.
Condon G. Putting a needle where it hurts. University of Connecticut Health Center website. Available at: http://today.uchc.edu/headlines/2005/may05/knees.html. Published May 17, 2005. Accessed February 23, 2011.
Divine JG, Zazulak BT, Hewett TE. Viscosupplementation for knee osteoarthritis: a systematic review. Clin Orthop Relat Res. 2007;455:113-122.
DynaMed Editorial Team. Degenerative joint disease of the knee. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php. Updated February 15, 2011. Accessed February 23, 2011.
Editorial staff and contributors. Osteoarthritis. EBSCO Health Library website. Available at: http://www.ebscohost.com/healthLibrary. Updated September 2010. Accessed February 23, 2011.
Joint aspiration. Cleveland Clinic website. Available at: http://my.clevelandclinic.org/services/joint%5Faspiration%5Finjection/hic%5Fjoint%5Faspiration%5Fand%5Finjection.aspx. Accessed February 24, 2011.
Jordan J. Comparison of four treatments for patients with severe knee cartilage damage. University of Wisconsin-Madison website. Available at: http://tc.engr.wisc.edu/uer/uer01/author1/content.html. Published June 17, 2011. Accessed February 23, 2011.
Viscosupplementation treatment for arthritis. American Academy of Orthopaedic Surgeons website. Available at: http://orthoinfo.aaos.org/topic.cfm?topic=a00217. Updated February 2009. Accessed February 23, 2011.
- Reviewer: Teresa Briedwell, DPT, OCS
- Review Date: 03/2013
- Update Date: 03/15/2013