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Principal Proposed Uses
What Is Ashwagandha Used for Today?
Interactions You Should Know About
Devi PU, Sharada AC, Solomon FE, et al. In vivo growth inhibitory effect of Withania somnifera (Ashwagandha) on a transplantable mouse tumour, Sarcoma 180. Indian J Exp Biol . 1992;30:169-172.
al-Hindawi MK, al-Khafaji SH, Abdul-Nabi MH. Anti-granuloma activity of Iraqi Withania somnifera . J Ethnopharmacol . 1992;37:113-116.
Kupparanjan K, et al. Effect of ashwaganda ( Withania somnifera Dunal) on the process of aging in human volunteers. J Res Ayurveda Siddha . 1980;1:247-258.
Bone K. [No title available]. MediHerb Professional Review . 1998;30.
Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol. 1998;50:1065-1068.
Archana R, Namasivayam A. Antistressor effect of Withania somnifera.J Ethnopharmacol. 1999;64:91-93.
Dhuley JN. Therapeutic efficacy of ashwagandha against experimental aspergillosis in mice. Immunopharmacol Immunotoxicol. 1998;20:191-198.
Ziauddin M, Phansalkar N, Patki P, et al. Studies on the immunomodulatory effects of Ashwagandha. J Ethnopharmacol. 1996;50:69-76.
Dhuley JN. Effect of ashwagandha on lipid peroxidation in stress-induced animals. J Ethnopharmacol . 1998;60:173-178.
Singh N, Nath R, Lata A, et al. Withania somnifera (ashwagandha), a rejuvenating herbal drug which enhances survival during stress (an adaptogen). Int J Crude Drug Res . 1982;20:29-35.
Dadkar VN, Ranadive NU, Dhar HL. Evaluation of antistress (adaptogen) activity of Withania somnifera (ashwagandha). Indian J Clin Biochem . 1987;2:101-108.
Dhuley JN. Adaptogenic and cardioprotective action of ashwagandha in rats and frogs. J Ethnopharmacol . 2000;70:57-63.
Singh B, Saxena AK, Chandan BK, et al. Adaptogenic activity of a novel, withanolide-free aqueous fraction from the roots of Withania somnifera Dun. Phytother Res . 2001;15:311-318.
Davis L, Kuttan G. Effect of Withania somnifera on DMBA induced carcinogenesis. J Ethnopharmacol. 2001;75:165-168.
Prakash J, Gupta SK, Kochupillai V, et al. Chemopreventive activity of Withania somnifera in experimentally induced fibrosarcoma tumours in Swiss albino mice. Phytother Res . 2001;15:240-244.
Russo A, Izzo AA, Cardile V, et al. Indian medicinal plants as antiradicals and DNA cleavage protectors. Phytomedicine . 2001;8:125-132.
Singh DD, Dey CS, Bhutani KK. Downregulation of p34cdc2 expression with aqueous fraction from Withania somnifera for a possible molecular mechanism of anti-tumor and other pharmacological effects. Phytomedicine . 2001;8:492-494.
Gupta YK, Sharma SS, Rai K, et al. Reversal of paclitaxel induced neutropenia by Withania somnifera in mice. Indian J Physiol Pharmacol . 2001;45:253-257.
Dhuley JN. Nootropic-like effect of ashwagandha ( Withania somnifera L .) in mice. Phytother Res . 2001;15:524-528.
Jain S, Shukla SD, Sharma K, Bhatnagar M. Neuroprotective effects of Withania somnifera Dunn . in hippocampal sub-regions of female albino rat. Phytother Res . 2001;15:544-548.
Bhattacharya SK, Bhattacharya A, Sairam K, et al. Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine . 2000;7:463-469.
Ahmad MK, Mahdi AA, Shukla KK, et al. Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males. Fertil Steril. 2010;94(3):989-996.
Khanna D, Sethi G, Ahn KS, et al. Natural products as a gold mine for arthritis treatment. Curr Opin Pharmacol. 2007;7(3):344-351.
Winters M. Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology. Altern Med Rev. 2006;11(4):269-277.
Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev. 2000;5(4):334-346.
As of 6/7/2011, additional research published on ashwagandha does not warrant any changes to this article.
- Reviewer: EBSCO CAM Review Board
- Review Date: 12/2015
- Update Date: 12/15/2015