Return to Index
Principal Proposed Uses
What Is Reishi Used for Today?
Bao X, Fang J, Li X. Structural characterization and immunomodulating activity of a complex glucan from spores of Ganoderma lucidum.Biosci Biotechnol Biochem. 2001;65:2384-2391.
Bao XF, Wang XS, Dong Q, Fang JN, Li XY. Structural features of immunologically active polysaccharides from Ganoderma lucidum.Phytochemistry. 2002;59:175-181.
van der Hem LG, van der Vliet JA, Bocken CF, et al. Ling Zhi-8: studies of a new immunomodulating agent. Transplantation. 1995;60:438-443.
Wang YY, Khoo KH, Chen ST, et al. Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities. Bioorg Med Chem. 2002;10:1057-1062.
Zhang J, Tang Q, Zimmerman-Kordmann M, Reutter W, Fan H. Activation of B lymphocytes by GLIS, a bioactive proteoglycan from Ganoderma lucidum.Life Sci. 2002;71:623-638.
Bao XF, Zhen Y, Ruan L, Fang JN. Purification, characterization, and modification of T lymphocyte-stimulating polysaccharide from spores of Ganoderma lucidum. . Chem Pharm Bull (Tokyo). 2002;50:623-629.
Lee JM, Kwon H, Jeong H, et al. Inhibition of lipid peroxidation and oxidative DNA damage by Ganoderma lucidum . Phytother Res. 2001;15:245-249.
Lu H, Kyo E, Uesaka T, Katoh O, Watanabe H. Prevention of development of N,N'-dimethylhydrazine-induced colon tumors by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male ICR mice. Int J Mol Med. 2002;9:113-117.
Lu H, Uesaka T, Katoh O, Kyo E, Watanabe H. Prevention of the development of preneoplastic lesions, aberrant crypt foci, by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male F344 rats. Oncol Rep. 2001;8:1341-1345.
Min BS, Gao JJ, Nakamura N, Hattori M. Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells. Chem Pharm Bull (Tokyo). 2000;48:1026-1033.
Wang SY, Hsu ML, Hsu HC, et al. The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. Int J Cancer. 1997;70:699-705.
Wu TS, Shi LS, Kuo SC. Cytotoxicity of Ganoderma lucidum triterpenes. J Nat Prod. 2001;64:1121-1122.
el-Mekkawy S, Meselhy MR, Nakamura N, et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum . Phytochemistry. 1998;49:1651-1657.
Eo SK, Kim YS, Lee CK, Han SS. Possible mode of antiviral activity of acidic protein bound polysaccharide isolated from Ganoderma lucidum on herpes simplex viruses. J Ethnopharmacol. 2000;72:475-481.
Eo SK, Kim YS, Lee CK, Han SS. Antiherpetic activities of various protein bound polysaccharides isolated from Ganoderma lucidum . J Ethnopharmacol. 1999;68:175-181.
Eo SK, Kim YS, Lee CK, Han SS. Antiviral activities of various water- and methanol-soluble substances isolated from Ganoderma lucidum . J Ethnopharmacol. 1999;68:129-136.
Kim YS, Eo SK, Oh KW, Lee C, Han SS. Antiherpetic activities of acidic protein-bound polysacchride isolated from Ganoderma lucidum alone and in combinations with interferons. J Ethnopharmacol. 2000;72:451-458.
Min BS, Nakamura N, Miyashiro H, Bae KW, Hattori M. Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chem Pharm Bull (Tokyo). 1998;46:1607-1612.
Oh KW, Lee CK, Kim YS, Eo SK, Han SS. Antiherpetic activities of acidic protein-bound polysacchride isolated from Ganoderma lucidum alone and in combinations with acyclovir and vidarabine. J Ethnopharmacol. 2000;72:221-227.
Yoon SY, Eo SK, Kim YS, Lee CK, Han SS. Antimicrobial activity of Ganoderma lucidum extract alone and in combination with some antibiotics. Arch Pharm Res. 1994;17:438-442.
Su C, Shiao M, Wang C. Potentiation of ganodermic acid S on prostaglandin E(1)-induced cyclic AMP elevation in human platelets. Thromb Res. 2000;99:135-145.
Tang W, Gao Y, Chen G, et al. A Randomized, Double-Blind and Placebo-Controlled Study of a Ganoderma lucidum Polysaccharide Extract in Neurasthenia. J Med Food. 2005;8:53-58.
Wicks SM, Tong R, Wang CZ, et al. Safety and tolerability of Ganoderma lucidum in healthy subjects: a double-blind randomized placebo-controlled trial. Am J Chin Med. 2007;35:407-414.
- Reviewer: EBSCO CAM Review Board
- Review Date: 12/2015
- Update Date: 12/15/2015