Notice: On December 18, 2025, Missouri Highlands Health Care acquired the Saint Francis Healthcare System Poplar Bluff campus and assets.
During the clinic and ancillary services transition, patients will continue to have access to healthcare services at this location. Saint Francis Healthcare System will operate services until January 30, 2026. Missouri Highlands Health Care is expected open at this location on February 2, 2026.
Please note the timeline and dates of the transition.
Saint Francis Pharmacy Poplar Bluff will transition to John’s Pharmacy on January 15, 2026. For more information contact John’s Pharmacy at 573-785-0984.
Saint Francis Clinic Poplar Bluff providers will see patients in Poplar Bluff up to January 23, 2026. This change does not affect any other Saint Francis clinic locations in Southeast Missouri.
Saint Francis Clinic Poplar Bluff Urgent Care services will operate until January 30, 2026, along with Imaging and Laboratory Services.
Black River Ambulatory Surgery Center will close permanently on January 23, 2025.
To request your records, please contact Saint Francis Health Information Management (HIM) Department at:
- Address: 211 Saint Francis Drive, Cape Girardeau, Missouri 63703
- Phone: 573-331-5120
- Email: roi@sfmc.net
- Website: https://www.sfmc.net/patients-visitors/medical-records/
Billing Inquiries
For billing-related assistance, you may contact Saint Francis Patient Financial Services at 573-331-5217 option 1, or email customerservice@sfmc.net.
For information concerning Missouri Highlands Health Care providers and other services please call 573-663-2313 or visit their website.
At Saint Francis Medical Center Poplar Bluff, we are here to help keep you and your family healthy for life. Many of our physicians, nurses, technicians and staff were raised in Poplar Bluff and the surrounding area. With years of experience, a commitment to medical excellence and a strong focus on your individual needs, we strive to provide high-quality care while bringing you an exceptional patient experience. Our objective is to improve the quality of healthcare in Poplar Bluff while keeping it affordable and accessible to all consumers.
As a Medical Partner of Saint Francis Healthcare System, Saint Francis Medical Center Poplar Bluff gives patients direct access to the latest technology and breakthroughs in cardiac care, neurosciences, cancer care, obstetrics and gynecology, neonatal care, emergency and trauma care, orthopedics and more.
Services
- Family medicine: primary care for every member of the family – from children to older adults
- Internal medicine: primary care for adults
- On-site laboratory
- Ancillary services including X-ray, bone densitometry and patient monitoring
Saint Francis Clinic Poplar Bluff
Saint Francis Clinic Poplar Bluff promotes patient health through regular checkups, screenings, patient education and preventive care for all ages and provides urgent care coverage for patients aged 2 and up.
Saint Francis Behavioral Health Poplar Bluff
The providers at Saint Francis Behavioral Health Poplar Bluff have the breadth of experience in behavioral health to understand and provide optimal care for each patient.
Saint Francis Pharmacy Poplar Bluff
Saint Francis pharmacies provide the following comprehensive services:
- Patient medication profile reviews
- Computerized screening for drug interactions
- Drug counseling with pharmacists
- Drug compliance history report
- Printed drug information sheets on most prescriptions
- Third-party automatic billing
- Printed prescription list for tax documentation upon request
- Automatic refills
- Drive-thru service available
Pharmacy Hours
Monday – Friday: 8 am – 6 pm
Saint Francis General Surgery Poplar Bluff
Saint Francis General Surgery Poplar Bluff provides surgical services to the Poplar Bluff and surrounding areas.
Saint Francis Imaging Poplar Bluff
Our leading-edge imaging department offers the most advanced technology available in the region, along with exceptional care, personal attention and seamless scheduling. We utilize state-of-the art diagnostic equipment, including the Hologic Selenia Dimension system for 3-D mammography and 3-D Affirm Biopsy System — the most reliable in the industry. Operated by experienced, licensed technologists, this technology provides the highest-quality images for exceptional diagnostics.
Dedicated to quality and excellence, our experienced team has a reputation for providing superb imaging and thoughtful patient care. As an American College of Radiology (ACR) accredited facility, we offer the gold standard in medical imaging to the patients we serve. We are also certified under the Mammography Quality Standards Act (MQSA).
We offer the following tests:
- 3-D Mammography
- 3-D Biopsy
- Computer Tomography (CT)
- Digital Mammography
- Magnetic Resonance (MRI)
- Nuclear Medicine
- Ultrasound
- General Radiology
To schedule your 3-D mammogram, call 573-778-2637. Walk-ins are also welcome.
Poplar Bluff Neurology Specialists
Poplar Bluff Neurology Specialists provides a full spectrum of neurological care for both inpatients and outpatients, including diagnosis, management and treatment of complicated disorders and injuries of the brain and nervous system.
